
Duke's talk show appearance is cancelled to allow television stations to cover the alien invasion, so Duke retires to the Duke Cave. Unlike previous encounters, the aliens initially appear peaceful and at first seem to pose no harm to the humans of Earth. On his way to the show, Duke witnesses a news broadcast on a nearby television screen announcing that aliens have once again invaded. The game begins with Duke sampling a video game based on his past heroics, followed by a scheduled interview with a talk show host.

Duke Nukem is now a world-renowned icon, living in the penthouse of a Las Vegas casino with his casual partners, the Holsom twins.


The events in Duke Nukem Forever take place about twelve years after the conclusion of Duke Nukem 3D.
